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BarbatoVTaleviRBraunSMerollaASudhakaranSLongobardiSet al

You need to produce measurable, impactful changes in abdominal fat and see a corresponding shift in metabolic markers

The combination therapy showed slightly better scores in WOMAC and Lequesne indices than HA alone, but not enough to support strong clinical superiority (Nouri et al., 2022)