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Description

Iron metabolism and ferroptosis may induce neurological damage through interactions with the central nervous system, gut microbiota, and brain-gut axis, positioning them as potential therapeutic targets for depression (Figure 3)

10.1172/JCI169986 152 MooreK

Concurrently, they can also unearth drugs with novel modes of action through the design and synthesis of new compounds

study demonstrated that ipamorelin: Released GH in a dose-dependent manner Did not significantly elevate cortisol levels, even at high doses Did not significantly elevate prolactin levels Did not significantly affect ACTH, FSH, LH, or TSH (4) This selectivity gives ipamorelin a notably clean side-effect profile compared to other GH secretagogues