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Relationship between residual cerebral blood flow and oxygen metabolism as predictive of ischemic tissue viability: sequential multitracer positron emission tomography scanning of middle cerebral artery occlusion during the critical first 6 hours after stroke in pigs

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& Kalafat, E

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In turn, mtDNA triggers cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS), which elevates secondary messenger cyclic 23-cGAMP generation that initiates stimulator of interferon genes (STING), leading to IRF3 and IRF7 activation [187, 188]

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The high reproducibility and the strong effect of SAAR on rodent lipid metabolism spurred clinical studies to combat obesity and MetS (Olsen et al., 2020

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