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Lastly, the ubiquitination level of the p53 protein was observed and the images were captured with an ECL imaging system from Thermo Fisher Scientific (US)

Although moderate intake has little effect on the general population, individuals who are genetically predisposed or have a preexisting tendency to glaucoma may be at increased IOP and risk of developing the disease, suggesting that caffeine restriction should be considered in this population

Thus, GSH homeostasis disturbance and GSH-dependent enzymes inactivation lead to the breakdown of the main protective barrier against ROS and as a result, the cell becomes more vulnerable to the damage caused by OS [6]

Abramson, J., Adler, J., Dunge, Jack., Evans, R., Green, T., Pritzel, A., Ronneberger, O., Willmore, L., Ballard, A