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For instance, a recent randomized controlled trial demonstrated that adjuvant therapy with xanthohumol in critically ill COVID-19 patients with acute respiratory failure significantly reduced the 28-day mortality rate (from 48% to 20%) and effectively suppressed crucial inflammatory and coagulopathy markers, including IL-6 and D-dimer ( To ensure the scientific rigor of this review, it is essential to clearly distinguish between the concepts of natural medicines and natural products. Although traditional medicine often employs crude extracts or compound formulations, the complexity of their constituents and batch-to-batch variability frequently obscure well-defined pharmacological mechanisms

Docetaxel induces Bcl-2- and pro-apoptotic caspase-independent death of human prostate cancer DU145 cells