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Description

Rb1 reduces Ca 2+ leakage caused by overactivated ryanodine receptor 2 (RyR2) and increases Ca 2+ uptake by sarcoplasmic reticulum Ca 2+ -ATPase 2a (SERCA 2a)

Bioinformatics 2020

The d-Galactosamine (GalN) and lipopolysaccharide (LPS) treatment that results in hepatic inflammation and subsequent fulminant hepatic failure in mice decreases the liver GSH content which is attenuated by hemin [haem oxygenase-1 (HO-1) inducer], but zinc protoporphyrin [(HO-1) inhibitor] reverses the effects of hemin [59]