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Cisplatin exposure directly induces follicle loss, while metformin treatment encourages the resumption of follicular growth and development in the ovaries, showing that primordial follicles and growing follicles are largely restored and atretic follicles are significantly reduced in cisplatin-treated ovaries

doi: 10.1152/physrev.00049.2019 127 PujariR.BanerjeeG

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