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For retatrutide , phase 2 data published in the New England Journal of Medicine (2023) demonstrated substantial mean weight reductions over 48 weeks in adults with obesity among the highest figures reported for any pharmacological agent to date

3.5.4 Monocyte chemoattractant protein 1 (MCP-1) Monocyte chemoattractant protein 1 is a chemokine that promotes the recruitment of monocytes and the spread of inflammation