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They can be synthesized and delivered as drugs, often by injection

Itraconazole prolonged survival compared to that achieved with fluconazole at certain dosages

Also, fragmented mitochondria and mitochondrial proteins (i.e., 48-kDa protein) have been found in the stone core matrices and thus may get involved in the stone nidus formation (Govindaraj and Selvam, 2001, 2002)