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For B12: monthly for wellness, or weekly for 48 weeks to correct confirmed deficiency

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Taking a proton pump inhibitor or other medications that reduce stomach acid for reflux or ulcers, as well as taking metformin for diabetes, can reduce absorption of B12 in food or supplements

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MMA levels dropped from 0.27 mol/L in the loading dose group and 0.30 mol/L in the no loading dose group to approximately 0.20 mol/L at days 30 and 90

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