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Therefore, 30 patients diagnosed with HF were given 1000 mg NR twice a day for 12 weeks, which increased whole blood NAD + levels and corresponded with higher peripheral blood mononuclear cells (PMBCs) mitochondrial respiration and reduced ROS production 318

Results: Colorectal cancer persister cells, which were enriched in the residual cancer cell population, exhibited reduced drug sensitivity, were largely quiescent and expressed high levels of stem cell-related genes and mesenchymal markers but not epithelial markers

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