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This problem could worsen as climate change reduces soil selenium levels gradually [26]

The frequency of B12 injections varies, but typically ranges from weekly to monthly

Increases above normal ranges should prompt evaluation

Numerous ex vivo organ culture studies and large animal models, including rats, rabbits, dogs, and pigs, have demonstrated that minimally invasive injection or percutaneous implantation of hydrogels loaded with transforming growth factor-3, anti-apoptotic miRNA, or autologous mesenchymal stem cells can maintain IVD height, restore its viscoelastic storage modulus, and delay or even partially reverse tissue degeneration (Yang S