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Regular use has also been linked to increased blood pressure in some studies

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The crystallization condition suitable for screening at the Diamond Light Source XChem facility was identified by optimizing the conditions previously reported ( 2.2 Fragment Screening Experiment and Structure Solution A total of 381 fragments from the DSI poised library ( (500 mM stock concentration dissolved in DMSO) were transferred directly to TbTR crystallization drops using an ECHO liquid handler (50 mM nominal final concentration) and soaked for 12 h before harvesting

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