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The next step should be reassessment, not only dose escalation

Prolonged toll-like receptor signaling by Mycobacterium tuberculosis and its 19-kilodalton lipoprotein inhibits gamma interferon-induced regulation of selected genes in macrophages

et al., 2021a), The loss of function of the Rb protein (a tumor suppressor protein) is an important event during liver carcinogenesis, yet the mechanisms involved are complex

Ketogenic diet alongside with therapies against pancreatic cancer A ketogenic diet, characterized by low carbohydrate and protein intake and high fat consumption, induces the production of ketone bodies and decreases glucose and insulin levels, mimicking fasting conditions without the need for calorie restriction