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2 Animal models for CIPN studies Animal models are frequently used to study the pathogenesis of CIPN and more importantly, to evaluate the drug efficacy in preventing or reversing CIPN symptoms (Hoke and Ray, 2014)

Fluorescence Polarization Assay Peptides functionalized with N-terminal 5-carboxyfluorescin (FAM) were synthesized by Genscript

Preclinical studies have examined how oxytocin receptor activation influences the hypothalamic-pituitary-adrenal axis, cortisol responses to social stressors, and amygdala reactivity in animal models

However, dedicated investigations into its role in tumor-associated mitochondrial transfer are still lacking, and further research is required to establish its therapeutic relevance in cancer