Figure 1 Virus-induced cell death leads to the loss of both infected and adjacent cells while releasing large amounts of damage-associated molecular patterns (DAMPs, such as High Mobility Group Box 1(HMGB1), Adenosine Triphosphate (ATP), and mitochondrial DNA(mtDNA)) and pathogen-associated molecular patterns (PAMPs) (14), which continuously activate macrophages, dendritic cells, and neutrophils
Disclosures: Chinmay Bera: Nothing to Disclose, Nashla Hamdan: Nothing to Disclose, Heather Kosick: Nothing to Disclose, Nader Allam: Nothing to Disclose, Mina Fakhriyehasl: Nothing to Disclose, Kartik Jhaveri: Nothing to Disclose, Keyur Patel: Novo-Nordisk: Consultant, Gilead Sciences: Consultant, Merck: Consultant, Resalis: Advisor 615 DIABETES IS A RISK FACTOR FOR SARCOPENIA OF PATIENTS WITH METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS-DRIVEN CIRRHOSIS Shinya Sato 1 Hiroaki Takaya 1 NORIHISA NISHIMURA 1 KOSUKE KAJI 1 Tadashi Namisaki 1 Takemi Akahane 1 Hitoshi Yoshiji 1 , 1 Nara Medical University Background: The relevance of metabolic disorders in causing liver diseases led the recent proposal by the international expert panel to rename the fatty liver as Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD)
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doi: 10.1167/iovs.61.10.49 363 WangCWangKLiP
