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The ectoenzymatic activity of CD38 is independent of its receptor functions [1] and leads to synthesis of cADPR and NAADP from NAD and NADP, respectively, thereby producing key secondary messengers that mobilize calcium from intracellular stores and regulate calcium signaling [4, 7,8,9]

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(The 503A Bulks List is a list of drug substances that the FDA has approved for compounding under section 503A of the Federal Food, Drug, and Cosmetic Act.) If the peptides meet the safety requirements, the committee will recommend reclassifying them onto this list, so they can then be legally prescribed and compounded