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The most common cause of bone spurs on the spine is osteoarthritis that causes joint damage due to arthritic changes

It is important to consider that prolonged high cholesterol diet (HCD) can lead to chronic systemic inflammation, resulting in an increased accumulation of dysfunctional and senescent immune cells ( Additionally, elevated levels of circulating cytokines could further impair immune cell function, weakening the overall immune response against cancer

The quality of care and economic burden of COPD in the United States: considerations for managing patients and improving outcomes

Then the overall framework of this article was summarized (Figure 1C)