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J Cosmet Dermatol 24:e70393 Wang L et al (2020) Asiaticoside produces an antidepressant-like effect in a chronic unpredictable mild stress model of depression in mice, involving reversion of inflammation and the PKA/pCREB/BDNF signaling pathway

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The copper complex itself is not optional decoration: the copper ion is what activates the receptor signaling at fibroblast surfaces

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