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Several studies have investigated CAT polymorphism and its involvement in the development of various diseases as well as its role as regulator in the CAT gene expression

National Library of Medicine (2022)

Altered endocrine, cytokine signaling and oxidative stress: a plausible reason for differential changes in testicular cells in diet-induced and genetically-inherited obesity in adult rats

This protocol was chosen due to its demonstrated capacity to generate iHLOs with high CYP enzyme activity, particularly CYP3A4, which is crucial for our subsequent compound or drug metabolism and toxicology evaluations