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Conclusion and Outlooks Accordingly, available data indicate that ROS detoxification pathways are not present to the extent they might remove all ROS from the cellular environment, but that there is a level of coordination between the processes which generate ROS and those which remove them, therefore, maintaining the optimal amount of ROS within the cellular environment

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de Souza HM, Borba-Murad GR, Ceddia RB, Curi R, Vardanega-Peicher M, Bazotte RB

The criteria excluding from further studies were: blood glucose concentration below 70 mg/dL and above 150 mg/dL and poor general condition (lethargy, lack of appetite, or any signs of illness)