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Since NF-B is expressed in almost every type of cell, including microglia, neurons, and astrocytes, its functions in various tissues and cells may have a major influence on systemic inflammatory responses

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(128) vacuum cooling treatment and various storage conditions, including cold rooms and modified atmosphere packaging, affected antioxidant enzyme activity in Agaricus bisporus mushrooms, revealing that vacuum-cooled mushrooms exhibited enhanced activity of antioxidant enzymes like superoxide dismutase, catalase, peroxidase and polyphenoloxidase along with a reduction in malondialdehyde levels and the generation of superoxide anions

Hence the need for Vitamin C supplements becomes necessary