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Numerous studies have proved that carotenoid biosynthesis is regulated by a variety of transcription factor families, including the R2R3-MYB, MADS-box, NAC, bHLH, SBP-box, AP2/ERF, HD-ZIP, NF-Y, and WRKY ( (Rin) , non-ripening ( Nor ), and colorless non-ripening (Cnr) promote our current understandings of the mechanisms underlying fruit ripening ( SlSGR1 and SlGgpps2 genes and activating their expression ( SlAPRR2 and SlGLK1 genes in tomato increased the number of plastids in fruit and carotenoid accumulation in fruit at ripening stage was higher than that of wild type ( SlNAC1 in tomato resulted in up-regulation of the expression of SIPSY1 and accumulation of total carotenoids

J., et al., Risk of Neurodegenerative Diseases in Patients With Inflammatory Bowel Disease: A Nationwide Populationbased Cohort Study, J Crohns Colitis 16, no

Some scientific observations suggest that excessively high levels of free zinc (well beyond normal supplemental ranges) could potentially interfere with certain glutathione-related enzymes

Nalwa HS, Barwal TS, Chugh P, Singh N, Jain N, Duggal L, Ganguly NK, Chaturvedi V, Mittal SA (2025) High prevalence of methotrexate intolerance in rheumatoid arthritis patients: a cross-sectional study