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Weichmann and Rohdewald, 2020)

As expected, since MTT and CTG assays measure cellular metabolism, the CC 50 values of both compounds were somehow lower in the various cell types as compared to growth curve assessment

By knocking out Acsl4 in renal tubules in vivo and in primary PTECs in vitro, we confirmed its critical role in oxalate-induced ferroptosis and kidney injury