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Pros The most sensitive configuration Low solvent usage Can be used for very complex mixtures Cons Low robustness and reliability Frequently suffers from ion suppression so signals have less linearity Easy to overload and contaminate Needs longer runs dues to longer equilibration times Possible modifications Low flow standard Decreasing the column diameter and flow rate can help address some of the issues of higher flow systems and a common term used for this is microflow

When consulting with patients, healthcare professionals should consider the thoughts and feelings of patients when making decisions about therapy

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