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In summary, our study supports that MeCbl, a widely prescribed drug, is promisingly repurposed to be an effective therapeutic option to GSDME dependent liver failure, which is characterized with high morbidity and high mortality without efficient clinical therapies

Izquierdo M, Lutz J, Galindo J, Morales-Cardenas A, Carrillo J (2020) Paradoxical Reaction to the Antituberculous Drugs in a Patient Without HIV Infection

This outcome would typically require three to four months of recovery, making the acceleration nothing short of astonishing to observers

Nod factor is structurally similar to fungal cell wall chitin, which is a known activator of the plant immune response (Pusztahelyi, 2018)