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The increased concentration of LBPs reached its peak after 24 h of administration, primarily identified in the liver

14 Even people who are not occupationally exposed carry certain metals in their body as a result of exposure from other sources, such as food, beverages, or air

Delivered via pH-sensitive nanoparticles, it is selectively released in the acidic penumbra, where it competitively inhibits mitochondrial SDH, thereby blocking reverse electron transport and reducing ROS, a key trigger of NLRP3 inflammasome activation and lipid peroxidation [218]

While mild dehydration might respond to oral rehydration, moderate to severe cases require the rapid replenishment that only IV therapy can provide