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The heavy subunit (molecular weight about 73 kDa) exhibits the catalytic activity of the native enzyme and is also responsible for the feedback inhibition by GSH

79 Trials eventually restarted when once-daily dosing in dogs showed a lower incidence of CPK elevations

Given both the extent of disability caused by age-related cataract and its costs, $5 to $6 billion per year 26 (Congressional Testimony of S.J

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