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However, it has been reported that the upregulation of mitophagy mediated by parkin might be related to mitochondrial damage in cardiac stem cells (human cardiac progenitor cells/hCPCs)

Coronary atherosclerosis initiates with endothelial damage to the vascular intima, followed by a sequence of events including lipid deposition, vascular smooth muscle cell proliferation, and extracellular matrix synthesis, collectively resulting in arterial wall thickening and progressive luminal narrowing (17)

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Morphine promotes phosphorylation of the human delta-opioid receptor at serine 363