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Bardoxolone methyl improves survival and reduces clinical measures of kidney injury in tumor-bearing mice treated with cisplatin

doi: 10.1210/endo.132.6.8504756

those whose skin has deteriorated since moving to Japan

These mechanisms collectively reduce estradiol levels and destabilize the hypothalamic-pituitary-ovarian axis, resulting in irregular cycles and a more symptomatic perimenopause (Matikainen et al., 2001)