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This mismatch between what the digestive system is doing and what the nervous system anticipates triggers nausea signals through the vagus nerve and brainstem emetic centers

Access this article Similar content being viewed by others Abbreviations 5-HT: 5-hydroxytryptamine or serotonin ACTH: corticotropin AGRP: agouti gene-related protein CART: cocaine- and amphetamine-regulated transcript CCK: cholecystokinin CGRP: calcitonin gene-related peptide CNS: central nervous system CRH: corticotropin-releasing hormone DRG: dorsal root ganglion DSIP: delta sleep-inducing peptide GABA: -amino-butyric acid GLP-1: glucagon-like peptide 1 GPCR: G-protein-coupled receptor IAPP: islet amyloid polypeptide LGV: large granular vesicle LHRH: luteinizing hormone-releasing hormone -MSH: -melanocyte-stimulating hormone NO: nitric oxide NPY: neuropeptide tyrosine PACAP: pituitary adenylyl cyclase-activating peptide PHI: peptide histidine isoleucine PP: pancreatic polypeptide PCR: polymerase chain reaction PNS: peripheral nervous system PYY: peptide tyrosine tyrosine SP: substance P SSV: small synaptic vesicle TGN: trans-Golgi network TRH: thyrotropin-releasing hormone VIP: vasoactive intestinal polypeptide References Agnati LF, Fuxe K, Benfenati F, Battistini N, Harfstrand A, Hkfelt T, Cavicchioli L, Tatemoto K, Mutt V (1983) Failure of neuropeptide Y in vitro to increase the number of alpha 2-adrenergic binding sites in membranes of medulla oblongata of the spontaneous hypertensive rat

11 Cancer Research Cancer cells exhibit a unique metabolic phenotype known as the Warburg effect, characterized by increased glycolysis even in the presence of oxygen, which is supported by elevated NAD+ levels