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NF-B signaling promotes fibrosis by activating fibroblasts and inducing the expression of fibrogenic factors like TGF-, which drives ECM production and fibroblast activation (Ren et al., 2024

direct bilirubin rarely exceeds 50% of total bilirubin in horses with cholestasis

TB-500 is primarily used for tissue repair and recovery, with the strongest clinical application in tendon and ligament injuries, muscle strains, post-surgical healing, and chronic inflammation

In April 2005 the US Food and Drugs Administration (FDA) approved a synthetic version, called exenatide, to treat type 2 diabetic patients unable to sufficiently control their blood sugar levels with other diabetic medications like metformin, and sulfonylureas