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Patients with severe pneumonia exhibit marked inter-individual variation in gut microbiome composition, driven by genetic, lifestyle, and environmental factors

The identified genes were categorized into three groups: 1) genes likely involved in housekeeping functions manifesting pleiotropic effects on multiple metabolites, 2) genes previously known to be involved in pathways for metabolites, and 3) novel genes which we have now genetically linked to specific metabolic pathways for metabolites

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