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Previous MRS studies have used the ratio of excitatory (Glu) and inhibitory (GABA) neurotransmitters as a proxy index of E/I balance in cortical networks and recent work found a positive correlation between GABA and Glx in medial parietal cortex 54 , consistent with electrophysiological evidence 55

Specifically, thiamine is important for glucose metabolism [51] and type 2 diabetics have been observed to have lower-than-average thiamine levels, suggesting that some degree of thiamine deficiency may play a role in the onset of diabetes

Stimulant Laxatives (Senokot, Correctol, Dulcolax, etc) deplete potassium, calcium, and vitamin D

Cell , 187 (9), 22882304.e27