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Link Wang, H., et al

The SURPASS and SURMOUNT programs collectively demonstrate tirzepatide as a transformative therapy for cardiometabolic disease

Front Pharmacol 2021;12:627533

Third, the discovery that MOTS-c also plays roles in immune regulation, particularly in suppressing innate immune overactivation, has opened research directions in inflammation-driven aging, autoimmunity, and potentially long-term sequelae of infections