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Description

Identification of novel antioxidant gene signature to predict the prognosis of patients with gastric cancer

Clinical description All patients with 5-oxoprolinase deficiency have been identified because of 5-oxoprolinuria (4 to 10 g/day

doi: 10.1016/j.biopha.2022.113386

Additionally, CD3+ immune cell depletion via a-CD3 antibody especially in the -M-POU2F1 model reversed the phenotype, suggesting a strong immune dependence of these TFs in promoting tumor clearance