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Research by Jorgensen et al

Each spray is prepared with: Normal Saline (pH 6.0) as the base solution Benzalkonium Chloride (BKC) as a preservative to inhibit microbial growth Lab-grade distilled water for consistent purity This eliminates the variability introduced by manual reconstitution and provides optimized stability from the manufacturer

Cholestyramine, an anion-exchange resin, may bind to acidic drugs, such as the thiazide diuretics in the GI tract, and decrease their absorption and therapeutic effectiveness

Fetal bradycardia may occur in 20 to 30 percent of patients receiving paracervical nerve block anesthesia with the amide-type local anesthetics and may be associated with fetal acidosis