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So the observation that these two domains, the clotting domain and inflammatory domain were not overlapping, was really the foundation of this invention was that we could maybe create this antibody to be able to target them in a selective way

Metabolic syndrome and related disorders

For HIV-associated lipodystrophy, a 2009 study found that 120 g/kg biweekly treatment showed an improvement in visceral adipose tissue by 1015% over 24 weeks, but further development was not pursued [wong (2008) abstract]

It is one of the few compounds shown to stimulate collagen organization , which is essential for tendon integrity