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New agents, such as tetrathiomolybdate salts, are currently being investigated in clinical trials, and genetic therapies are being tested in animal models

Importance of redox potential for the in vivo function of the cytoplasmic disulfide reductant thioredoxin from Escherichia coli

Neuroimmunomodulation 16:201207 Landi D, Vollaro S, Pellegrino G, Mulas D, Ghazaryan A, Falato E, Pasqualetti P, Rossini PM, Filippi MM (2015) Oral fingolimod reduces glutamate-mediated intracortical excitability in relapsing-remitting multiple sclerosis