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Conversely, iron chelation strategies, using agents such as deferiprone, deferoxamine, and deferasirox, may be beneficial in early-stage or iron-addicted tumours by limiting proliferation and reducing oxidative damage to surrounding tissues (101104)

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The upregulation of Mfn2 suggests an additional mechanism through which CBD exerts its anti-inflammatory effects, promoting an environment conducive to neuroprotection while limiting inflammatory responses mediated through microglial activation

[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Price L, Wilson C, Grant G