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Treatment with L-carnitine at a dose of 300 mg/kg showed more powerful antioxidant effects than the lower dose (150 mg/kg) concerning GSH levels in the prefrontal cortex and hippocampus and hippocampal MDA levels

In experimental colitis models, ERS inhibitors such as sodium phenylbutyrate can significantly improve intestinal inflammation, indicating the important role of the ER stress PERK axis in IBD (101)