glutathione peroxidase enzyme mimetics

glutathione peroxidase enzyme mimetics peroxidase-like functions of 1,2-diselenane-4,5-diol and its amphiphilic derivatives: Switchable catalytic cycles depending on peroxide substrates The Role of Glutathione Peroxidase-1

Name: glutathione peroxidase enzyme mimetics peroxidase-like functions of 1,2-diselenane-4,5-diol and its amphiphilic derivatives: Switchable catalytic cycles depending on peroxide substrates The Role of Glutathione Peroxidase-1
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The Role of Glutathione Peroxidase 1 in Health and Disease PMC The glutathione peroxidase family: Discoveries and mechanism ScienceDirect Functional Mimics of Glutathione Peroxidase: Bioinspired Synthetic Antioxidants Accounts of Chemical Research A validated method to assess glutathione peroxidase enzyme activity Chemical Papers Springer Nature Link

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For example, evidence suggests that oestrogens have a protective effect on mitochondria, so their blockage (e.g., through aromatase inhibitors or antioestrogens) can disrupt this protective function [53]

TG, triglycerides

A notable challenge is that many strategies demonstrating promising results in animal models show diminished efficacy when translated to human clinical trials