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Various mechanisms could disrupt the metabolic balance between glucose and lipids such as dysregulation of the hypothalamicpituitaryadrenal (HPA) axis 20,21 , insulin resistance 22 , infection 23 , hypoxia 3 , micro hemorrhage, gut dysbiosis, and thereby the gut-brain axis 24,25

Together, these facts highlight the need for effective interventions to curb the spread of this silent epidemic

Some protocols involve continuous administration for 6-12 months with periodic assessment and dose adjustment

Minimally invasive real time monitoring of mitochondrial NADH and tissue blood flow in the urethral wall during hemorrhage and resuscitation