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drilled into the head of every smug high school science student

Estrogen synthesis and signaling pathways during aging: From periphery to brain

Paolicelli, R

Thus, targeting of the transporters expressed only at the BBB would be useful in terms of delivery of drugs with extracellular targets in the brain, while utilization of the transporters expressed at the BBB and cellular membrane of the brain parenchymal cells is essential for delivery of the drugs with intracellular targets