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J Physiol Pharmacol 62(1):29 Yu LM, Di WC, Dong X, Li Z, Zhang Y, Xue XD, Xu YL, Zhang J et al (2018) Melatonin protects diabetic heart against ischemia-reperfusion injury, role of membrane receptor-dependent cGMP-PKG activation

Neurodegeneration in MS seems to be driven by a complex interplay between compartmentalized neuroinflammation, oxidative stress, iron toxicity and mitochondrial dysfunction, and occurs as early as the radiologically and clinically isolated syndrome stages