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Both variants had similar kinetic parameters as the WT, indicating that though catalytically unchanged, the stability of these variants is markedly reduced, with G6PD Plymouth present in even lower amounts and ultimately leading to more severe clinical manifestations

All experiments detailed here complied with the regulations formulated by the Institutional Animal Care and Use Committee (IACUC, No

However, they also secrete pro-inflammatory cytokines, such as TNF- and IL-6, which exacerbate inflammatory responses and facilitate atherosclerosis progression (103)