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How to innovate and optimize the safety and efficacy of treatment in clinical practice, while ensuring they are affordable for patients with sarcopenia, remains a critical issue that needs to be addressed

Celecoxib-induced gastrointestinal, liver and brain lesions in rats, counteraction by BPC 157 or L-arginine, aggravation by L-NAME

61,62 The acetylation of p53 at certain sites hinders the phosphorylation of several serines located in the p53 NTD, which activates genes with high p53 affinity, including CDKN1A