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Tumor-derived EV metabolites, such as succinate and glycolytic enzymes, influence metabolic reprogramming and the tumor microenvironment, but mechanistic data linking EV-mediated metabolic transfer to inflammation-driven colorectal carcinogenesis are still developing (Haque et al., 2025

Effects of various extracts of N

In parallel, dihydroorotate dehydrogenase (DHODH) and sulfide:quinone oxidoreductase (SQOR) were shown to generate ubiquinol (CoQ 10 H 2 , reduced) within mitochondria using dihydroorotate and selenide, respectively 23,24