Vol. XVIII · Free shipping $75+ · Read the collection
Feature · Product Review
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Description

Notably, by blocking voltage-dependent L-type calcium channels, nimodipines beneficial effects are likely mediated through mechanisms other than vasospasm reduction: inhibition of CSDs, antithrombotic effects (diminished platelet aggregation and increased endogenous fibrinolysis), anti-inflammatory properties, and some neuroprotective effects (less endothelin neurotoxicity, less intracellular swelling, less oxygen free radicals, and less intracellular Ca 2+ -influx) (12, 64, 65)

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