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To quantify the SCFA concentrations in the colonic luminal contents, the samples were homogenised with 150 mm-NaHCO 3 (pH 78) (1:5, w/v) in an Ar atmosphere

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Ethics statement The animal study was reviewed and approved by Naval Medical University Animal Welfare and Ethics Committee

34 NF-B signaling pathway Nuclear factor-kappa B (NF-B) transcription factors are critical regulators of immunity, stress responses, apoptosis and differentiation